Service
Polynucleotides (PDRN ) / Croma & Rejuran
Procedure Time
30 mins - 1 hour
Downtime
Almost none
To Treat
Smooth fine lines and wrinkles
treatments
A course of three treatments is recommended.
Results last
The rejuvenating result lasts for one to three months.
What is REJURAN?
REJURAN®, also known as Rejuran Healer or Rejuran I, is an advanced dermal rejuvenation treatment made from wild salmon-derived polynucleotide (PN) DNA fragments, extracted using proprietary DOT (DNA Optimizing Technology).
Unlike traditional hyaluronic acid-based skin boosters, REJURAN® harnesses bio-active DNA molecules that stimulate the skin’s natural regeneration process, repairing damaged tissue and reducing inflammation.
By boosting fibroblast activity, REJURAN® promotes long-term collagen and elastin production, improving skin texture, elasticity, and hydration. It effectively addresses a range of concerns, including uneven skin tone, fine lines, enlarged pores, acne scars, and excessive oil production.
REJURAN® is included in the Australian Register of Therapeutic Goods (ARTG) and is trusted in over 20 countries worldwide.
What is PN (Polynucleotide)?
REJURAN®, also known as Rejuran Healer or Rejuran I, is an advanced dermal rejuvenation treatment made from wild salmon-derived polynucleotide (PN) DNA fragments, extracted using proprietary DOT (DNA Optimizing Technology).
Unlike traditional hyaluronic acid-based skin boosters, REJURAN® harnesses bio-active DNA molecules that stimulate the skin’s natural regeneration process, repairing damaged tissue and reducing inflammation.
By boosting fibroblast activity, REJURAN® promotes long-term collagen and elastin production, improving skin texture, elasticity, and hydration. It effectively addresses a range of concerns, including uneven skin tone, fine lines, enlarged pores, acne scars, and excessive oil production.
REJURAN® is included in the Australian Register of Therapeutic Goods (ARTG) and is trusted in over 20 countries worldwide.
What is REJURAN® Used For?
REJURAN® is a versatile skin treatment that helps to rejuvenate and repair the skin at a cellular level. It is commonly used to:
- Address skin texture and elasticity
- Minimise the appearance of fine lines and wrinkles
- Address acne scars and other superficial scarring
- Address skin hydration and radiance
- Refine pore size and oil production
- Even out uneven skin tone
- Support skin barrier function and reduce redness
By stimulating fibroblast activity, REJURAN® encourages the production of collagen and elastin — two essential proteins that contribute to skin health.
REJURAN® for Pigmentation Concerns
While REJURAN® is not designed to lighten pigmentation in the same way as hydroquinone or laser therapy, it can help reduce the appearance of pigmentation over time by improving overall skin health.
At Chroma Dermatology, we may recommend REJURAN® as part of a broader pigmentation treatment plan. This may be particularly useful for:
- Post-inflammatory hyperpigmentation (e.g., following acne, eczema, or cosmetic treatments)
- Skin barrier damage that contributes to pigmentation
- Inflamed, reactive skin types
REJURAN® works by calming inflammation, supporting skin regeneration, and strengthening the barrier, all of which can help reduce pigment formation and fade existing discolouration more effectively when combined with other therapies.
Who is REJURAN® Suitable For?
REJURAN® is suitable for a wide range of skin types and concerns, making it an excellent option for individuals seeking skin treatment without drastic procedures. It is particularly beneficial for those experiencing:
- Early signs of ageing
- Acne scarring
- Dehydrated or dull skin
- Enlarged pores
- Uneven skin tone
REJURAN® Treatment Plan
A typical Rejuran treatment plan includes three to four sessions spaced two to four weeks apart. Maintenance every three to six months can help prolong the results.
Some temporary swelling or redness is common after each session. This usually settles quickly, and most people return to their normal routine within a day.
FAQs
Some patients notice improvements in skin texture and hydration within a few weeks. Optimal results are usually observed after completing the full treatment course
REJURAN® is a dermal injectable treatment that contains polynucleotides (PNs), which are purified DNA fragments derived from wild salmon. It is typically used to support skin repair, hydration, and improvement in skin texture. The treatment is often considered for individuals seeking options to address early signs of ageing, such as fine lines or mild textural changes. It may be included as part of a broader skin care plan after a clinical assessment.
Each session typically lasts between 30 to 60 minutes, including preparation and treatment time.
Yes, Rejuran is biocompatible and generally safe for all skin types, including sensitive and darker skin tones.
REJURAN® is generally suitable for a range of skin types, including individuals with darker skin tones. However, suitability is assessed on a case-by-case basis. At Chroma Dermatology, a consultation is required to determine whether REJURAN® is appropriate based on your skin type, treatment goals, and medical history. Chroma’s Melbourne team has specific experience treating patients with skin of colour, which is an important focus of our clinic.
The number of sessions can vary depending on your individual needs and skin response. In many cases, an initial series of two to three sessions spaced 3-4 weeks apart is recommended. Some individuals choose to continue with maintenance treatments every 6–12 months. Chroma’s Melbourne team will discuss a personalised plan during your consultation, including expected outcomes and any risks associated with the procedure.
Absolutely. Rejuran can be part of a comprehensive skin rejuvenation plan, including treatments like lasers, microneedling, and topical agents.